MBLI’s Annexin V apoptosis detection kit is based on the observation that phosphatidylserines (PS) translocate from the inner membrane to the outer membrane during apoptosis. Annexin V binds to PS on the outer membrane. This event can be easily detected using MBLI’s kit using conventional dye-staining along with any streptavidine or avidin-dye reagents.
Annexin V and PI cannot be bound to cell membrane and DNA respectively
Annexin V bind to PS which is exposed to the outer membrane, but PI cannot be intruded to cells
Annexin V bind to PS which is exposed to the outer membrane, and PI interacts with double stranded DNA
Cytochemistry (double staining of FITC-Annexin V and Pl) using MEBCYTO® Apoptosis Kit (Annexin V-FITC Kit) (Code No. 4700)
| Code No. | Name | Size | Notes |
|---|---|---|---|
|
MEBCYTO® Apoptosis Kit (Annexin V-FITC Kit)
|
100 tests
|
Highly Cited
|
Learn more about other popular Apoptosis targets and products
GENERAL APOPTOTIC PRODUCTS
MBL International offers over 600 products including proteins, antibodies and kits to aid in the study of the apoptotic pathway. These products cover a wide variety of applications.
DNA FRAGMENTATION DETECTION
The TdT-mediated dUTP-biotin nick end labeling method (TUNEL method) enables in situ visualization of DNA fragmentation at the single cell level by labeling the terminal ends of nucleic acids. The MEBSTAIN Apoptosis Kit Direct is an apoptosis detection kit based on the TUNEL method.
CASPASE ACTIVITY ASSAY
Apoptosis is primarily induced by the activation of caspases. Active caspases recognize a large number of different substrates, leading to the activation of several different apoptotic pathways.
APOPTOSIS MAIN PAGE
Apoptosis, a form of programmed cell death, is not only a major process within normal homeostasis but is present in disease states such as cancer and many autoimmune and neurodegenerative diseases.
